<sub id="7xzf7"></sub>

            <thead id="7xzf7"></thead>
            <address id="7xzf7"></address>

              ENGLISH | 院長信箱 | 書記信箱
              師資隊伍
              孫桂鴻

              1、職稱職務: 教授,博士生/碩士生導師

              undefined

              2、學科專業: 病原生物學、微生物學

              3、研究方向: 病毒感染免疫與腫瘤

              4、實驗室位置:基礎醫學院1號樓3樓東312室

              5、聯系電話: 13307180026

              6、Email: ghsunlab@whu.edu.cn

              7、學習經歷:

              1990.09~1994.06 武漢大學,攻讀學士學位

              2001.09~2006.06 武漢大學,攻讀碩士、博士學位

              8、主要工作經歷與任職 :

              1994.07~2013.05 武漢大學基礎醫學院結構中心,講師,副教授

              2008.10~2010.10 美國國立衛生研究所(NIH),訪問學者

              2013.05~2016.10 武漢大學微生物教研室,副教授

              2016.11~至今    武漢大學微生物教研室,教授

              9、目前主要科學研究領域和興趣:

              病毒感染免疫及其致病機理:主要聚焦病毒感染、免疫逃逸和被免疫清除過程中,病毒與宿主之間的相互作用,以及相互作用后導致的不同腫瘤的分子機理。

              利用小分子調控病毒復制和腫瘤的產生: 主要目標是嘗試利用小分子RNA、小分子多肽等干擾病毒感染和復制,抑制腫瘤的產生。

              10、教學情況:

              分別給臨床五、七、八年制學生,口腔五、八年制學生,健康學院護理班、護理國際班和全球健康學生,藥學院學生講授《醫學微生物學》 《病原生物學》 《微生物學》 和《生物醫學制藥工程課程》等課程;參與《臨床微生物學》《病原生物學》研究生課程的教學。參編國家級規劃教材和配套教輔教材,公開發表教學論文2篇,并獲武漢大學教學論文三等獎。指導的研究生獲國家獎學金5人次,獲國家創新獎一等獎1人次。指導大學生創新實驗項目5項(國家級一項),其中多名本科生參與發表SCI論文多篇。

              11、主要社會兼職

              曾受邀擔任The FASEB Journal、BBA、J Cancer、Journal of Cellular and Molecular Medicine和PLoS One等多種SCI雜志審稿專家,教育部學位與研究生教育評估專家,以及國家自然科學基金評審專家。擔任2015級臨床8年制3班的班級導師,2016獲得武漢大學“燭光導航工程”優秀導航師。

              12、近5年代表性論文(近5年第一作者或通訊作者):

              1. Wang J, Chen J, Liu Y, Zeng X, Wei M, Wu S, Xiong Q, Song F, Yuan X, Xiao Y, Cao Y, Li C, Chen L, Guo M, Shi YB, Sun G*, Guo D*. Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR-192-3p-XIAP via NF-κB Signaling. Hepatology. 2019; 69(3):974-992.

              2. Song F, Wei M, Wang J, Liu Y, Guo M, Li X, Luo J, Zhou J, Wang M, Guo D, Chen L*, Sun G*. Hepatitis B virus-regulated growth of liver cancer cells occurs through the microRNA-340-5p-activating transcription factor 7-heat shock protein A member 1B axis. Cancer Sci. 2019; 110(5):1633-1643.  

              3. Wang J, Sun G*. The function of autophagy in diseases caused by hepatitis B virus. Chinese Science Bulletin, 2019; 64( 30): 3109-3122.in Chinese)

              4. Guo Y, Wang J, Yuan S, Guo S, Liu D, Sun G*. The regulation of HBx in hepatitis B virus replication. Chinese Science Bulletin, 2019; 64( 30): 3101-3108. in Chinese)

              5. Xiong Q, Wu S, Wang J, Zeng X, Chen J, Wei M, Guan H, Fan C, Chen L*, Guo D*, Sun G*. Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression. Cell Biosci. 2017; 7:16.

              6. Liu Z, Song F, Ma ZL, Xiong Q, Wang J, Guo D, Sun G*. Bivalent Copper Ions Promote Fibrillar Aggregation of KCTD1 and Induce Cytotoxicity. Sci Rep. 2016; 6:32658.

              7. Sun G*, Roediger J, Shi YB. Thyroid hormone regulation of adult intestinal stem cells: Implications on intestinal development and homeostasis. Rev Endocr Metab Disord. 2016; 17(4):559-569.

              8. He M, Lin Y, Tang Y, Liu Y, Zhou W, Li C, Sun G*, Guo M*. miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells. Aging (Albany NY). 2016l; 8(7):1442-56.

              9. Sun G, Fu L, Wen L, Shi YB. Activation of Sox3 gene by thyroid hormone in the developing adult intestinal stem cell during Xenopus metamorphosis. Endocrinology. 2014; 155(12):5024-32.

              10. Luu N, Wen L, Fu L, Fujimoto K, Shi YB*, Sun G*. Differential regulation of two histidine ammonia-lyase genes during Xenopus development implicates distinct functions during thyroid hormone-induced formation of adult stem cells. Cell Biosci. 2013; 3(1):43.

              11. Sun G, Fu L, Shi YB. Epigenetic regulation of thyroid hormone-induced adult intestinal stem cell development during anuran metamorphosis. Cell Biosci. 2014; 28; 4:73.

              12. Liu Z, Xiang Y, Sun G*. The KCTD family of proteins: structure, function, disease relevance. Cell Biosci. 2013; 24; 3(1):45.

              13. Sun G, Heimeier RA, Fu L, Hasebe T, Das B, Ishizuya-Oka A, Shi YB. Expression profiling of intestinal tissues implicates tissue-specific genes and pathways essential for thyroid hormone-induced adult stem cell development. Endocrinology. 2013; 154(11):4396-407.


              江苏快三软件