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              ENGLISH | 院長信箱 | 書記信箱
              師資隊伍
              熊海蓉

              1、職稱職務副教授,碩士生導師5449

              2、學科專業:病原生物學

              3、研究方向:病毒感染的致病機制與防治技術研究

              4、實驗室位置:基礎醫學院醫學病毒學研究所1樓

              5、Email:hrxiong@whu.edu.cn

              6、學習經歷:

              1997.9-2002.6 武漢大學醫學院, 醫學學士

              2002.9-2009.6 武漢大學基礎醫學院, 病原生物學系,博士

              2005.6-2009.3 Medical College of Georgia,聯合培養博士

              7、主要工作經歷與任職:

              2009.7-2012.11 武漢大學基礎醫學院 講師

              2012.12-至今 武漢大學基礎醫學院 副教授

              8、目前主要科學研究領域和興趣:

              從事病毒感染的致病機制與防治技術研究,主要包括人類免疫缺陷病毒(HIV)和漢坦病毒(HV)等多種病毒的感染與免疫機制研究、人類重要病毒性傳染?。℉FRS、AIDS等)的分子流行病學研究、抗病毒藥物研究(流感病毒、皰疹病毒、柯薩奇病毒、呼吸道合胞病毒、輪狀病毒、EV71、漢坦病毒等常見病毒)。

              9、主要學術兼職:

              10、教學情況:

              一直從事本科生和研究生的教學工作,現承擔的教學任務有全校通識課 (艾滋病防治、性傳播疾病與青春期健康)、本科生必修課(組織與功能、實驗室安全)以及研究生通開課(實驗室生物安全、高級分子與細胞生物學、生物醫學技術、臨床微生物學等)。

              11、獲獎及榮譽:

              12、近五年主要代表性論文:

              1. Li MK, Liu YY, Wei F, Shen MX, Zhong Y, Li S, Chen LJ, Ma N, Liu BY, Mao YD, Li N, Hou W, Xiong HR*, Yang ZQ*. Antiviral activity of arbidol hydrochloride against herpes simplex virus type in vitro and in vivo. International Journal of Antimicrobial Agents. 2018 Jan;51(1):98-106 (co-corresponding author)

              2. Chen QZ, Luo F, Lu MX, Li N, Teng Y, Huang QL, Zhu N, Wang GY, Yue M, Zhang Y, Feng Y, Xiong HR*, Hou W*. HTNV-induced upregulation of miR-146a in HUVECs promotes viral infection by modulating pro-inflammatory cytokine release. Biochemical and Biophysical Research Communications. 2017 Nov 4;493(1):807-813. ( co-corresponding author)

              3. Chen XP§, Xiong HR§, Zhu N, Chen QZ, Wang H, Zhong CJ, Wang MR, Lu S, Luo F, Hou W*. Lack of association between integrin αvβ3 gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China. Virologica Sinica. 2017 Feb;32(1):73-79.(co-first author)

              4. Liu YY, Chen LJ, Zhong Y, Shen MX, Ma N, Liu BY, Luo F, Hou W, Yang ZQ, Xiong HR*. Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo. Acta Pharmacologica Sinica. 2016 Apr;37(4):497-504

              5. Xiong HR, Zhang YH, Deng Kan, Liu Q, Liu YY, Luo F, Hou W, Yang ZQ*. Antiviral activity and mechanism of action of arbidol against Hantaan virus infection. Tropical Journal of Pharmaceutical Research. 2016; 15 (7): 1439-1445

              6. Liu Q§, Xiong HR§, Lu L, Liu YY, Luo F, Hou W, Zhan-Qiu Yang. Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection. Acta Pharmacologica Sinica. 2013 Aug 5;34(8):1075-83 (co-first author)

              7. Xiong HR, Shen YY, Lu L, Hou W, Luo F, Xiao H, Yang ZQ. The Inhibitory Effect of Rheum palmatum Against Coxsackievirus B(3)in Vitro and in Vivo. The American Journal of Chinese Medicine. 2012;40(4):801-12.

              8. Xiong HR, Lee RJ, Haura EB, Edward JG, Dynan WS, Li S. Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. International Journal of Radiation Oncology Biology Physics. 2012;Jul 1;83(3):1023-30.

              9. Xiong HR, Li Q, Chen W, Liu DY, Ling JX, Liu J, Liu YJ, Zhang Y, Yang ZQ. Specific Humoral Reaction of Hemorrhagic Fever with Renal Syndrome (HFRS) Patients in China to Recombinant Nucleocapsid Proteins from European Hantaviruses. European journal of clinical microbiology & infectious diseases.  2011 May;30(5):645-51.

              10. Xiong HR, Luo J, Hou W, Xiao H, Yang ZQ. The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo. Journal of ethnopharmacology, 2011 Jan 27;133(2):718-23.

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