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              ENGLISH | 院長信箱 | 書記信箱
              師資隊伍
              韓松

              1、職稱職務副教授、碩導undefined

              2、學科專業:病理生理學

              3、研究方向:神經免疫

              4、實驗室位置:基礎醫學院1號樓4樓

              5、Email:hansong@whu.edu.cn

              6、學習經歷:

              1999.09-2003.7 武漢大學生命科學學院,生物技術專業,本科

              2003.09-2008.7 武漢大學生命科學學院微生物專業,博士

              7、主要工作經歷與任職:

              2008.09~2011.03 武漢大學基礎醫學院,博士后

              2011.04~2016.12 武漢大學基礎醫學院,講師

              2017.01~至今  武漢大學基礎醫學院,副教授

              8、目前主要科學研究領域和興趣:

              從事神經系統自身免疫疾病的發病機制和治療研究,包括神經免疫疾病發病機制研究,靶向鉀離子通道的生物活性肽設計篩選及其作用機制,及藥用活性肽治療神經免疫疾病的臨床前基礎研究。先后主持國家級及省部級科研項目4項,公開發表SCI收錄學術論文10余篇。

              9、主要學術兼職:

              湖北省病理生理學會理事

              10、教學情況:

              承擔床臨醫學相關專業本科生、留學生和研究生的病理生理學相關理論和實驗課程的教學工作,包括《病理生理學》、《損傷與反應》、《機能學實驗二》、《臨床病理生理學》等課程的教學,公開發表教學論文1篇。

              11、獲獎及榮譽:

              12、近五年主要代表性論文:

              1. Inhibition of DPP4 enhances inhibitory synaptic transmission through activating the GLP-1/GLP-1R signaling pathway in a rat model of febrile seizures. Zhang Y, Liu Y, Xu J, Sun Q, Yu F, Cheng J, Peng B, Liu W, Xiao Z, Yin J, Han S*, He X. Biochem. Pharmacol. 2018 Oct;156:78-85.

              2. A Kv1.3 channel-specific blocker alleviates neurological impairment through inhibiting T-cell activation in experimental autoimmune encephalomyelitis. Yuan XL, Zhao YP, Huang J, Liu JC, Mao WQ, Yin J, Peng BW, Liu WH, Han S*, He XH*. CNS Neurosci Ther. 2018, doi: 10.1111/cns.12848. (Co-correspongding author)

              3. Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis. Huang J.#, Han S.#, Sun Q., Zhao Y., Liu J., Yuan X., Mao W., Peng B., Liu W., Yin J., He X., Cell Biosci. 2017, 7:31.

              4. Zhongcheng Wang, Yusong Zhang, Jian Fang, Fang Yu, Duanhe Heng, Yuanteng Fan, Jian Xu, Biwen Peng, Wanhong Liu, Song Han*, Xiaohua He*, Decreased methylation level of H3K27me3 increases seizure susceptibility. Mol Neurobiol. 2016, DOI 10.1007/s12035-016-0197-4. (Co-correspongding author)

              5. Zongyun Chen, Youtian Hu, Jun Hu, Weishan Yang, Jean-Marc Sabatier, Michel De Waard, Zhijian Cao, Wenxin Li, Song Han*, Yingliang Wu*, Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues. Biochem Biophys Res Commun. 2014, 447(1): 70-6. (Co-correspongding author)

              6. Jinzhi Lu, Xiong Chen, Yingying Zhang, Jian Xu, Lianglu Zhang, Zhi Li, Wanhong Liu,Jingping Ouyang, Song Han*, Xiaohua He*, Astragalus polysaccharide inducesanti-inflammatory effects dependent on AMPK activity in palmitate-treated RAW264.7 cells. Int J Mol Med. 2013, 31(6):1463-70. (Co-correspongding author)

              7. Jing Feng, Congya Yua, Mingyu Wang, Zhi Li, Yingliang Wu, Zhijian Cao, Wenxin Li , Xiaohua He, Song Han*, Expression and characterization of a novel scorpine-like peptide Ev37, from the scorpion Chaerilus tricostatus. Protein Expression and Purification. 2013, 88(1):127-33.

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